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dc.contributor.authorCelebi A.R.C.
dc.contributor.authorÖzbey, Caner
dc.contributor.authorMirza G.E.
dc.date.accessioned2019-08-01T13:38:39Z
dc.date.available2019-08-01T13:38:39Z
dc.date.issued2014
dc.identifier.issn0004-2749
dc.identifier.urihttps://dx.doi.org/10.5935/0004-2749.20140072
dc.identifier.urihttps://hdl.handle.net/11480/728
dc.description.abstractObjective: To determine and compare the mast cell count in primary and recurrent vascularized pterygium, and in normal bulbar conjunctiva. Methods: The study included 22 patients with primary pterygium (PP group) and 28 patients with vascularized recurrent pterygium (VRP group) that underwent excision via the limbal conjunctival autograft technique. Normal conjunctiva samples were collected from the superotemporal bulbar conjunctival region, just temporal to the site from which the autograft conjunctival tissue was harvested. The total number of mast cells in the pterygium (primary and recurrent) and control tissue samples was calculated microscopically using 1% toluidine blue stain under 400× magnification. Results: The mean mast cell count in primary and vascularized recurrent pterygium tissue was 7.45 ± 2.06 mm-2 and 16.11 ± 4.33 mm-2, respectively, and the difference was significant (independent samples t-test, P<0.001). The mean mast cell count in pterygium tissue was significantly higher than that in normal conjunctiva tissue in both groups (Student's t-test, P<0.001). Conclusion: An increase in the number of mast cells might play a role in the pathogenesis of recurrent pterygium. Determination of a mast cell count cut-off value could be of diagnostic significance for recurrent pterygium.en_US
dc.language.isoengen_US
dc.publisherConselho Brasileiro De Oftalmologiaen_US
dc.relation.isversionof10.5935/0004-2749.20140072en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectConjunctivaen_US
dc.subjectMast Cellsen_US
dc.subjectPterygium/Diagnosticen_US
dc.subjectRecurrenceen_US
dc.subjectToluidine chlorideen_US
dc.titleThe role of mast cells in vascularized recurrent pterygiumen_US
dc.typearticleen_US
dc.relation.journalArquivos Brasileiros de Oftalmologiaen_US
dc.contributor.departmentTıp Fakültesien_US
dc.identifier.volume77en_US
dc.identifier.issue5en_US
dc.identifier.startpage285en_US
dc.identifier.endpage287en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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